Other eating disorders aren’t nearly so resistant to treatment. The National Institutes of Health has devoted more than $100 million over the past decade to studying anorexia, yet researchers have not found a single compound that reliably helps people with the disorder. A 2020 review found people who have been hospitalized for the disease are more than five times likelier to die than their peers without it. Anorexia is well known to be the deadliest eating disorder the only psychiatric diagnosis with a higher death rate is opioid-use disorder.
ADD DISORDER RIBBON TRIAL
This was the only medication trial for treating anorexia that has shown any positive effect at all, Attia told me, and even then, the effects were “very modest.”ĭespite nearly half a century of attempts, no pill or shot has been identified to effectively treat anorexia nervosa. Those patients in her study who were on olanzapine increased their BMI a bit more than others who were taking a placebo, but the two groups showed no difference in their cognitive and psychological symptoms.
Patients with anorexia were still unable to bring themselves to eat, still stuck in rigid thought patterns, still chillingly underweight.Ī few years ago, a group led by Evelyn Attia, the director of the Center for Eating Disorders at New York Presbyterian Hospital and the New York State Psychiatric Institute, tried giving patients an antipsychotic drug called olanzapine, normally used to treat schizophrenia and bipolar disorder, and known to cause weight gain as a side effect. So did Prozac and SSRIs and atypical antidepressants.
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